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Nov 16,  · What is megacolon? Megacolon is the stretching and widening of your colon. Bowel movements build up in your colon instead of passing through to your rectum. Megacolon can be caused by a genetic condition. Most cases are sporadic, and some are familial megacolon and present during adolescence or adulthood. There is a need for diagnostic criteria and identifying genetic variants reported in non-Hirschsprung's dixckxx.xyz by: 4.

Inflammatory bowel disease, or IBD, is the most common initial cause of toxic megacolon. There are two main forms: ulcerative colitis (UC) and Crohn’s disease. Both these conditions involve an. What Is Megacolon? Megacolon is an abnormal dilation of the colon that is not caused by mechanical obstruction. It is usually accompanied by symptoms such as abdominal discomfort, but may result in serious complications (colonic perforation, peritonitis, and/or sepsis) if left untreated.

Objective: Chronic megacolon is rarely encountered in clinical practice beyond infancy or early childhood. Most cases are sporadic, and some are familial megacolon and present during adolescence or adulthood. There is a need for diagnostic criteria and identifying genetic variants reported in non-Hirschsprung’s megacolon. Megacolon is the term used for an abnormally enlarged colon. It is often associated with extra (redundant) loops of bowel. It can cause severe constipation. Megacolon can be congenital and is often hereditary, or can gradually develop over many years of poor diet, constipation and/or laxative abuse.